A steep phosphoinositide bis-phosphate gradient forms during fungal filamentous growth

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A steep phosphoinositide bis-phosphate gradient forms during fungal filamentous growth

Membrane lipids have been implicated in many critical cellular processes, yet little is known about the role of asymmetric lipid distribution in cell morphogenesis. The phosphoinositide bis-phosphate PI(4,5)P(2) is essential for polarized growth in a range of organisms. Although an asymmetric distribution of this phospholipid has been observed in some cells, long-range gradients of PI(4,5)P(2) ...

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Phosphatidylinositol-4-phosphate-dependent membrane traffic is critical for fungal filamentous growth.

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 2012

ISSN: 1540-8140,0021-9525

DOI: 10.1083/jcb.201203099